Bivalirudin Trifluoroacetate

Kedu ihe bụ Bivalirudin Trifluoroacetate?

Bivalirudin trifluoroacetate bụ ihe injinia, onye na-egbochi thrombin kpọmkwem nke a na-eji na mgbochi na ọgwụgwọ apoplexy. Ọ bụ ihe na-egbochi thrombin dị ike na nke akọwapụtara, ihe na-akpali akpali na coagulation juputara. Bivalirudin trifluoroacetate na-eduzi intravenously ma nwee mmalite ọrụ ngwa ngwa. Akụ na-eji ya ma nwee ọkara ịdị adị nke ihe dị ka nkeji iri abụọ na ise.

Ọ na-ejikọta na saịtị thrombin dị ike, na-eme ka ọ ghara ịgbanwe fibrinogen kpamkpam na fibrin. Nke a na-egbochi mmepe nke mkpụkọ ọbara. Na mgbakwunye, bivalirudin trifluoroacetate na-egbochi ịgbalite platelet, bụ ndị na-ahụ maka mmepe nke mkpụkọ ọbara.

Basic Ozi

Aha ngwaahịa: Bivalirudin Trifluoroacetate

CAS: 128270-60-0

MF:C98H138N24O33

MW: 2180.29

EINECS: 274-570-6

MDL Nọmba: MFCD08282793

Ịdị ọcha: 98%+

Ngwugwu: 1g,10g,25g,500g

Ejiri ya: nyocha na ọkwa pharma

Nkwụsi ike: Stable

Usoro usoro:

Usoro: D-Phe-Pro-Arg-Pro-Gly-Gly-Gly-Gly-Asn-Gly-Asp-Phe-Glu-Glu-Ile-Pro-Glu-Glu-Tyr-Leu-OH

Na-echekwa na: Ebe dị jụụ (2-8oC, pụọ na ọkụ)

Nkọwa na oke:

Ka anyị bido site n'inyocha nkọwapụta na oke nke Bivalirudin Trifluoroacetate. Ozi a dị oke mkpa maka ndị ọkachamara nọ n'ọhịa iji hụ na ojiji nke ziri ezi na nke dị irè. Biko rụtụ aka na tebụl dị n'okpuru maka nkọwa zuru ezu:

Chemical mejupụtara:

Ịghọta ihe mejupụtara kemịkalụ bụ ihe dị mkpa maka ndị ọkachamara na ngalaba ọgwụ na ọgwụ. Rụtụ aka na tebụl dị n'okpuru maka ndakpọ ihe ndị bụ isi:

Ọrụ na ọrụ:

Bivalirudin trifluoroacetate bụ ngwa ngwa thrombin inhibitor nke a na-eji na mgbochi na ọgwụgwọ apoplexy. Ọ bụ ihe na-egbochi thrombin dị ike na nke akọwapụtara, ihe na-akpali akpali na coagulation juputara. Bivalirudin trifluoroacetate ejikọta na saịtị thrombin siri ike, na-egbochi ya ịgbanwe fibrinogen kpamkpam ka ọ bụrụ fibrin. Nke a na-egbochi mmepe nke mkpụkọ ọbara. Na mgbakwunye, bivalirudin trifluoroacetate na-egbochi ịgbalite platelet, bụ ndị na-ahụ maka mmepe nke mkpụkọ ọbara.

A na-eji ya na ntọala ụlọ ọgwụ dị iche iche, gụnyere:

• Mgbasa mgbasa ọbara nke percutaneous (PCI): A na-eji ya egbochi apoplexy n'oge PCI, usoro a na-edobe stent n'ime akwara nwere oke iji nwee ọganihu n'ọbara.

• Ọnọdụ obi siri ike (ACS):A na-eji ya agwọ ACS, ọnọdụ nke enwere mbelata na-atụghị anya ya na iyi ọbara banye n'obi.

• Mmetụta nke obi (AF): N'ime ndị ọrịa nwere AF, ọnọdụ nke obi na-akụ n'oge ọ bụla, a na-eji ọgwụ mgbochi thrombosis bivalirudin trifluoroacetate.

• Apoplexy akwara miri emi (DVT): A na-eji ya agwọ DVT, ọnọdụ nke coagulation ọbara na-etolite n'ime akwara dị omimi, n'ozuzu na ụkwụ.

• Aspiratory embolism (PE): PE bụ ọnọdụ nke mkpụkọ ọbara na-esi na akwara miri emi gaa na ngụgụ ma na-agwọ ya na bivalirudin trifluoroacetate.

Usoro njikọ:

The njikọ usoro na-agụnye ọtụtụ mgbagwoju nzọụkwụ iji hụ na kasị elu àgwà nke Bivalirudin Trifluoroacetate. Ihe ndị bụ isi na-enweta mmeghachi omume nchịkwa, na-eduga n'ịmepụta ngwaahịa ikpeazụ. Usoro a gụnyere usoro njikwa mma siri ike iji mezuo ụkpụrụ mba ụwa.

• Ngwakọta peptide siri ike: A na-ejikọta akụkụ peptide ya site na iji peptide synthesis siri ike (SPPS). SPPS bụ usoro maka imepụta peptides nke a na-agbakọta peptide na nkwado siri ike, otu amino acid n'otu oge. A na-agbakwunye amino acid na nkwado siri ike n'usoro achọrọ, na amino acid ọ bụla na-ejikọta ya na agbụ peptide na-eto eto site na iji reagent njikọ. Ozugbo agbụ peptide zuru ezu, a na-agbaji ya site na nkwado siri ike ma dị ọcha.

• Trifluoroacetylation: A na-emezi peptide trifluoroacetylated ka ọ na-akpụzi bivalirudin trifluoroacetate. Trifluoroacetylation bụ okirikiri ebe a na-agbakwunye ụyọkọ trifluoroacetyl na N-njedebe peptide. A na-emekarị nke a site n'iji trifluoroacetic anhydride n'anya isi.

• Ọcha: A na-emetọ ngwaahịa ahụ site na iji usoro dị iche iche, dị ka chromatography na crystallization. Emechachara nke a iji kpochapụ mmebi ọ bụla site na ihe ọgwụ ahụ.

• Nwa: A na-ahazi ngwaahịa ahụ emebere ka ọ bụrụ usoro nha kwesịrị ekwesị, dịka azịza maka infusion. Nke a nwere ike ịgụnye ịgbakwunye ihe ndozi dị iche iche, dị ka cradles, additives, na stabilizers.

• Nnukwu nha nke peptide: Ọ bụ nnukwu peptide dị obere, nke nwere amino acid 20. Nke a na-eme ka ọ bụrụ ihe ịma aka ijikọ ọnụ karịa peptides dị ntakịrị.

• Ọnụnọ nke chiral dị iche iche na-elekwasị anya: Ọ nwere ọtụtụ nlebara anya chiral. Nke a bu n'obi na e nwere ọtụtụ stereoisomers nke ọgwụ. Ọ dị mkpa ijikọ stereoisomer ziri ezi, n'ihi na stereoisomer ndị ọzọ nwere ike ime mmetụta pụrụ iche ma ọ bụ ọbụna na-emerụ ahụ.

• Ihe achọrọ maka ezigbo ihe omume: Ọ kwesịrị ịbụ ezigbo omume dị elu nke ukwuu iji chekwaa ya na ihe na-akpali akpali. Nke a bụ n'ihi na ọbụna obere mmetọ nke mmetọ nwere ike imetụta ahụike na oke ọgwụ.

Ụkpụrụ Ogo ngwaahịa:

Bivalirudin trifluoroacetate bụ ihe ọgwụ, na ihe niile a tụlere, ọ kwesịrị imezu ụkpụrụ nduzi dị mma ka a ga-echebe na ịga nke ọma maka ndị ọrịa. Ndị ọkachamara nhazi setịpụrụ ụkpụrụ ịdịmma ndị a, dị ka US Food and Medicine Organisation (FDA) na European Meds Office (EMA).

Ụkpụrụ àgwà maka bivalirudin trifluoroacetate -agụnye:

• Amata: Ọgwụ kwesịrị ịbụ ihe a na-ekwu na ọ bụ. A na-anwale nke a mgbe niile site na iji usoro ezi uche dị iche iche, dị ka chromatography na spectroscopy.

• ọcha: Ekwesịrị ịwepụ ọgwụ ahụ n'ebe mgbada, dị ka ihe dị iche iche sịntetik, ihe mgbaze, na microorganisms. A na-anwale nke a mgbe niile site na iji usoro sayensị dị iche iche, dị ka chromatography na spectroscopy.

• Ike: Ọgwụ kwesịrị inwe ike ma ọ bụ omume nkịtị. A na-anwale nke a site n'iji nyocha eke dị iche iche.

• Safety: Ndị ọrịa ga-enwerịrị ike ịṅụ ọgwụ ahụ n'enweghị nsogbu. A na-anwale nke a site n'iji ihe okike dị iche iche na nyocha mmadụ.

Na mgbakwunye na ụkpụrụ ndị a n'ozuzu mma, bivalirudin trifluoroacetate ga-enwerịrị ụkpụrụ dị mma maka iji ya eme ihe.

Yihui na-edobe ụkpụrụ ịdị mma maka mmepụta Bivalirudin Trifluoroacetate. Usoro a na-akwado ISO, Kosher, Halal, na GMP asambodo, na-ahụ na ngwaahịa a na-ezute akara nrịbama zuru ụwa ọnụ. Asambodo ndị a na-egosi nraranye Yihui n'iwepụta ọgwụ nke kacha mma.

Ebe ntinye akwụkwọ na ụlọ ọrụ dị iche iche:

Bivalirudin Trifluoroacetate na-achọta ngwa na ụlọ ọrụ dị iche iche, nke kachasị n'ime ngalaba ahụike na ọgwụ. Ojiji ya na ọgwụgwọ ọgwụ mgbochi ọrịa na-eme ka ọ dị mkpa n'ụlọ ọgwụ, ụlọ ọgwụ na ụlọ ọrụ ahụike ndị ọzọ. Ọdịiche nke ngwaahịa a gbatịrị na ụlọ nyocha nyocha, na-enye aka na ọganihu na ọgwụ obi.

• Obi:A na-eji ya egbochi ma na-agwọ ọnya ọbara n'ime ndị ọrịa na-aga site na mgbasa ozi coronary percutaneous (PCI), dị ka nhazi stent. A na-ejikwa ya agwọ ọrịa obi siri ike (ACS), ọnọdụ na-agụnye ọdịda obi na akwara na-adịghị mma.

• Ọrịa: A na-eji ya egbochi mkpụkọ ọbara n'ime ndị ọrịa na-agafe carotid endarterectomy, usoro ahụike iji kpochapụ ihe ncheta na usoro carotid.

• Usoro ọgwụgwọ muscular: A na-eji ya egbochi mkpụkọ ọbara na ndị ọrịa na-aga usoro ahụike muscular, dị ka nnọchi hip na ikpere.

• Usoro ọgwụgwọ vaskụla: A na-eji ya egbochi ụyọkọ ọbara n'ime ndị ọrịa na-aga usoro ahụike vaskụla, dịka ọmụmaatụ, n'akụkụ usoro ahụike na ndozi aneurysm.

• Ndị ọzọ: A na-ejikwa ya egbochi ma na-agwọ ụyọkọ ọbara n'ime ndị ọrịa nwere fibrillation atrial (AF), apoplexy vein miri emi (DVT), na pneumonic embolism (PE).

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Ọrụ OEM:

Yihui na-enye ọrụ Onye nrụpụta ngwa mbụ (OEM), na-enye ihe ngwọta ahaziri iche iji mezuo ihe achọrọ. Nke a na-eme ka ndị ahịa nweta Bivalirudin Trifluoroacetate ahaziri maka mkpa ha pụrụ iche, na-eme ka Yihui dị ka onye mmekọ a pụrụ ịdabere na ya na ụlọ ọrụ ọgwụ.

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Yihui, onye nrụpụta ama ama na-ebubata ya Bivalirudin Trifluoroacetate, na-ebute ogo ngwaahịa na ndakọrịta n'ụkpụrụ mba ụwa. Site na asambodo dị ka ISO, Kosher, Halal, na GMP, Yihui na-eguzo dị ka ihe na-egosi ịdị mma. Maka ndị na-achọ ịzụrụ, kpọtụrụ Yihui ozugbo na sales@yihuipharm.com iji nweta oke nke izizi ọgwụ.